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Policies for the SDGs need to be designed keeping in mind how to reach the last individual in line, so that the most vulnerable are also the most sought after. These policies must be implemented with humane principles at their core. To deepen sustainability efforts, issues such as climate smart agriculture, biodiversity conservation and sustainable blue economy, and water conservation need to be addressed. For issues ranging from food and nutrition for all to universal digital access to inclusive healthcare to broad-based financial products, how can the G20 countries create/strengthen institutions and collaborations? These challenges may also include providing health infrastructure and holistic healthcare leveraging traditional systems of medicine. While gender outcomes remain a cause for concern, women-led development processes require significant policy support to promote entrepreneurship and allied fields so as to increase female labour force participation. Recent reversals in SDG achievement caused by the pandemic and the ensuing economic crisis have brought the focus back on societal resilience. Science, technology, and innovation, and technology facilitation for SDGs remain key means of implementation as outlined in the Addis Ababa Action Agenda (AAAA) and the Agenda 2030. Hence, revitalising the modalities of development cooperation in its various forms remains critical to the attainment of the SDGs by 2030.